隋森芳-凯发k8
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隋森芳-凯发k8

教授,博士生导师
中科院院士

1964-1970 清华大学精密仪器系,学士
1978-1981 清华大学工程物理系,硕士
1985-1988 德国慕尼黑工业大学生物物理所,博士
1989-1991 清华大学生物科学与技术系,副教授
1991.1-至今 清华大学生命科学学院(2009年9月以前为生物科学与技术系),教授、博导

● 研究兴趣、领域:

我们利用冷冻电子显微学,结合生物化学、生物物理学和细胞生物学等技术手段,研究:
(1)蛋白质复合体、复杂蛋白质机器和膜蛋白的结构、功能与工作机制;
(2)囊泡运输中的分子机制,蛋白质与膜脂的相互作用,生物膜与重大疾病的关系。

 

● 代表性论文:

1. ma j, you x, sun s, wang x, qin s, sui sf*. (2020) structural basis of energy transfer in porphyridium purpureum phycobilisome. nature, 579(7797):146-151.
2. pi x, zhao s, wang w, liu d, xu c, han g, kuang t*, sui sf*, shen jr*. (2019) the pigment-protein network of a diatom photosystem ii-light-harvesting antenna supercomplex. science, 365(6452). pii: eaax4406.
3. huang x, sun s, wang x, fan f, zhou q, lu s, cao y, wang qw, dong mq, yao j, sui sf*.(2019)mechanistic insights into the snare complex disassembly. sci adv.,5(4).
4. qin x, pi x, wang w, han g, zhu l, liu m, cheng l, shen jr, kuang t*, sui sf*. (2019) structure of a green algal photosystem i in complex with a large number of light-harvesting complex i subunits. nat plants, 5(3):263-272.
5. pi x, tian l, dai he, qin x, cheng l, kuang t, sui sf*, shen jr*. (2018) unique organization of photosystem i-light-harvesting supercomplex revealed by cryo-em from a red alga. proc natl acad sci usa, 115(17):4423-4428.
6. yang x, yang f, wang w, lin g, hu z, han z, qi y, zhang l, wang j, sui sf*, chai j*. (2018) structural basis for specific flagellin recognition by the nlr protein naip5. cell research, 28(1):35-47.
7. zhang j, ma j, liu d, qin s, sun s*, zhao j, sui sf*. (2017) structure of phycobilisome from the red alga griffithsia pacifica. nature, 551(7678):57-63.
8. sun s, li l, yang f, wang x, fan f, yang m, chen c, li x, wang hw, sui sf*. (2017) cryo-em structures of the atp-bound vps4-e233q hexamer and its complex with vta1 at near-atomic resolution. nat commun., 8:16064.
9. hu z, zhou q, zhang c, fan s, cheng w, zhao y, shao f, wang hw, sui sf*, chai j*. (2015) structural and biochemical basis for induced self-propagation of nlrc4. science, 350(6259):399-404.
10. chang l, liu x, li y, liu cc, yang f, zhao j*, sui sf*. (2015) structural organization of an intact phycobilisome and its association with photosystem ii. cell research, 25(6):726-737.

● 凯发k8的联系方式:

电话: 86-10-62792083/62784768
e-mail: suisf@mail.tsinghua.edu.cn
lab website: http://suilab.life.tsinghua.edu.cn/

 

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