戚益军-凯发k8
教授
1991-1995,南京农业大学,本科
1995-1998,原浙江农业大学,硕士
1998-2001,浙江大学,博士
2001-2004,美国俄亥俄州立大学,博士后
2004-2006 ,美国冷泉港实验室,博士后
2006-2011,北京生命科学研究所,研究员、高级研究员
2011-至今,清华大学生命科学学院,副教授、教授
● 研究兴趣、领域:
植物rna生物学和表观遗传。主要研究:1)植物中rna调控的生物学功能和作用机制;2)表观遗传信息的跨代传递机制;3)rna和表观遗传调控在作物重要农艺性状形成中的作用。
● 开设的课程:
高级植物生物学、rna生物学
● 代表性论文:
1. xie, d.#, chen, m.#, niu, j.#, wang, l., li, y., fang, x., li, p. and qi, y.* (2021) phase separation of serrate drives dicing body assembly and promotes mirna processing in arabidopsis. nature cell biology, 23: 32-39. highlighted in nature cell biology, 23:3-10, 2021
2. jiang, p.#, lian, b.#, liu, c., fu, z., shen, y., cheng, z.* and qi, y.* (2020) 21-nt phasirnas direct target mrna cleavage in rice male germ cells. nature communications, 11:5191
3. fang, x.#, zhao, g.#, zhang s., li, y., gu, h., li, y., zhao, q. and qi, y.* (2019) chloroplast-to-nucleus signaling regulates microrna biogenesis in arabidopsis. developmental cell, 48: 371-382
4. liu, c.#, xin, y.#, xu, l.#, cai, z., xue, y., liu, liu, c., xin, y., xu, l., cai, z., xue, y., liu, y., xie, d., liu, y. and qi, y.* (2018) arabidopsis argonaute1 binds chromatin to promote gene transcription in response to hormone and stress stimuli. developmental cell, 44 (3): 348-361. highlighted in developmental cell 44: 277-279, 2018
5. ye, r. #, chen, z. #, lian, b., rowley, m., xia, n., chai, j., li, y., wierzbicki a., and qi, y.* (2016) a dicer-independent route for biogenesis of sirnas that direct dna methylation in arabidopsis. molecular cell, 61: 222-235.
6. fang, x., cui, y., li, y., and qi, y.* (2015) transcription and processing of primary mirnas are coupled by elongator complex in arabidopsis. nature plants, doi:10.1038/nplants.2015.75.
7. gao, m. #, wei, w. #, li, m. #, wu, y., ba, z., jin k.-x., li, m.-m., liao, y.-q., adhikari s., chong, z., zhang, t., guo, c.-x., tang, t.-s., zhu, b.-t., xu, x.-z., mailand, n., yang, y.*, qi, y.*, and rendtlew danielsen, j. (2014) ago2 facilitates rad51 recruitment and dna double-strand break repair by homologous recombination. cell research,24:532-541.
8. wu, x., shi, y., li, j., xu, l., fang, y., li, x., and qi, y.* (2013). a role for the rna-binding protein mos2 in microrna maturation in arabidopsis. cell research,23: 645-657.
9. ye, r. #, wang, w. #, iki, t., liu, c., wu, y., ishikawa m., zhou, x., and qi, y.* (2012). cytoplasmic assembly and selective nuclear import of arabidopsis argonaute4/sirna complexes. molecular cell, 46: 859-870. highlighted in molecular cell 46: 719-721, 2012
10. wei, w. #, ba, z. #, gao, m., wu, y., ma, y., amiard, s., white, c., danielsen, j., yang, y., and qi, y.* (2012). a role for small rnas in dna double-strand break repair. cell, 149:101-112. highlighted in nature review genetics 13:299, 2012; nature reviews molecular cell biology 13: 282, 2012; and nature structural & molecular biology 19: 470, 2012 recommended on faculty of 1000 ( )
11. wang, w. #, ye, r. #, xin, y., feng, x., li, c., zhou, x., and qi, y.* (2011). an importin β protein negatively regulates microrna activity in arabidopsis. the plant cell, 23: 3565-3576. (cover story)
12. wu, l. #, zhou, h. #, zhang, q., ni, f., liu, c., and qi, y.* (2010). dna methylation mediated by a microrna pathway. molecular cell, 38: 465-475. (cover story) highlighted in cell, 141: 556, 2010.
13. wu, l., zhang, q., zhou, h., ni, f., wu, x., and qi, y.* (2009). rice microrna effector complexes and targets. the plant cell, 21: 3421-3435.
14. mi, s. #, cai, t. #, hu y., chen y., hodges e., ni f., wu l., li s., zhou h., long c., chen s., hannon g., and qi, y.* (2008) sorting of small rnas into arabidopsis argonaute complexes is directed by the 5’ terminal nucleotide. cell, 133: 116-127. this work was featured in cell 133:25-26, 2008.
15. zhao, t. #, li, g. #, mi, s., li, s., hannon, g., wang, x.-j.*, and qi, y*. (2007). a complex system of small rnas in the unicellular green alga chlamydomonas reinhardtii. genes and development, 29: 1190-1203. (*co-corresponding authors) highlighted in: cell 129:1029, 2007; genes and development 21: 1153-1156, 2007; nature 447: 5, 2007; nature 447: 518, 2007; nature review genetics 8: 406, 2007; acs chemical biology 2: 436-437, 2007
● 荣誉、奖励:
2010年获谈家桢生命科学创新奖
2013年获中国青年科技奖
2016年获国家自然科学奖二等奖(第一完成人)
2017年获首届全国创新争先奖状
● 凯发k8的联系方式:
地址:北京市海淀区清华大学生物技术馆4101-4106
e-mail: qiyijun@tsinghua.edu.cn