刘玉乐-凯发k8
教授
1984.9-1988.7 天津南开大学生物化学专业 (学士)
1990.9-1992.6 北京中国科学院微生物学研究所 (硕士)
1994.9-1997.11 中国科学院微生物学研究所与英国苏格兰作物研究所联合培养博士
1988.8-1998.9 北京中国科学院微生物学研究所 实习,助理,副研究员,研究员
1995.5-1996.5 英国苏格兰作物研究所 访问学者
1998.9-1999.8 美国德克萨斯大学奥斯丁分校 博士后
1999.9-2002.8 美国耶鲁大学 博士后
2002.9-2006.12 美国耶鲁大学 associate research scientist
2007.1 ---至今 清华大学 教授,“百人计划”责任教授
● 研究兴趣、领域:
植物免疫的信号传导与调控、植物病毒病理的分子基础、植物细胞自噬、植物功能基因组。
● 代表性论文:
1. gong q, wang y, he l, huang f, zhang d, wang y, wei x, han m, deng h, luo l, cui f, hong y, liu y*. molecular basis of methyl-salicylate-mediated plant airborne defence, nature 622(7981):139-148, 2023
2. yang m, ismayil a, jiang z, wang y, zheng x, hong y, li d*, liu y*. a viral protein disrupts vacuolar acidification to facilitate virus infection in plants, embo journal 41(2): e108713, 2022
3. wang y, gong q, wu y, huang f, ismayil a, zhang d, li h, gu h, ludman m, fátyol, qi y, yoshioka k, hanley-bowdoin l, hong y, liu y*. a calmodulin-binding transcription factor links calcium signaling to antiviral rnai defense in plants, cell host & microbe 29, 1393–1406, 2021
4. li h, zhang d, xie k, wang y, liao q, hong h, liu y*. efficient and high-throughput pseudorecombinant-chimeric cucumber mosaic virus-based vigs in maize. plant physiology 187(4):2865-2876, 2021
5. wang j, chen t, han m, qian l, li j, wu m, han t, cao j, nagalakshmi u, rathjen jp, hong y, liu y*. plant nlr immune receptor tm-22 activation requires nb-arc domain-mediated self-association of cc domain. plos pathogens 16(4):e1008475, 2020
6. ismayil a, yang m, haxima y, wang y, li j, han l, wang y, zheng x, wei x, nagalakshmi u, hong y, hanley-bowdoin l, liu y*. cotton leaf curl multan virus βc1 protein induces autophagy by disrupting the interaction of autophagy related protein 3 with glyceraldehyde-3 phosphate dehydrogenases. plant cell 32(4):1124-1135, 2020
7. ismayil a, haxim y, wang y, li h, qian l, han t, chen t, jia q, yihao liu a, zhu s, deng h, gorovits r, hong y, hanley-bowdoin l, liu y*. cotton leaf curl multan virus c4 protein suppresses both transcriptional and post-transcriptional gene silencing by interacting with sam synthetase. plos pathogens 14(8): e1007282, 2018
8. haxim y, ismayil a, jia q, wang y, zheng x, chen t, qian l, liu n, wang y, han s, cheng j, qi y, hong y, liu y*, autophagy functions as an antiviral mechanism against geminiviruses in plants. elife 6, e23897., 2017
9. xu g, wang s, han s, xie k, wang y, li j, liu y*, plant bax inhibitor-1 interacts with atg6 to regulate autophagy and programmed cell death. autophagy 13(7):1161-1175, 2017
10. jia q, liu n, xie k, dai y, han s, zhao x, qian l, wang y, zhao j, gorovits r, xie d, hong y and liu y*, clcumub βc1 subverts ubiquitination by interacting with nbskp1s to enhance geminivirus infection in nicotiana benthamiana, plos pathogens 12(6): e1005668, 2016
11. wang y, zheng x, yu b, han s, guo j, tang h, deng h, hong y and liu y*, disruption of microtubules in plants suppresses macroautophagy and triggers starchy chloroplast autophagy, autophagy 11(12): 2259-74, 2015
12. han s,wang y, zheng x, jia q, zhao j, bai f,hong y and liu y*, cytoplastic glyceraldehyde-3-phosphate dehydrogenases interact with atg3 to negatively regulate autophagy and immunity in nicotiana benthamiana, plant cell 27(4):1316-31, 2015
13. du y, zhao j, chen t, liu q, zhang h, wang y, hong y, xiao f, zhang l, shen q and liu y*, type i j-domain nbmip1 proteins are required for both tobacco mosaic virus infection and plant innate immunity, plos pathogens 9(10): e1003659, 2013.
14. wang y, yu b, zhao j, guo j, li y, han s, huang l, du y, hong y, tang d, and liu y*,autophagy contributes to the leaf starch degradation, plant cell 25(4): 1383-1399, 2013
15. liu y, schiff m, czymmek k, talloczy z., levine b and dinesh-kumar sp. autophagy regulates programmed cell death during the plant innate immune response, cell 121(4), 567-577, 2005
● 荣誉、奖励及参加学术团体的情况:
1997年,中国科学院青年科学家奖获得者
2007年,清华大学“百名人才引进计划” 责任教授
● 凯发k8的联系方式:
电话: 86-10-62794013
e-mail:yuleliu@mail.tsinghua.edu.cn