教授 博士生导师，中国科学院院士
1964-1970 清华大学精密仪器系，学士
1978-1981 清华大学工程物理系，硕士
1985-1988 德国慕尼黑工业大学生物物理所，博士
1989-1991 清华大学生物科学与技术系，副教授
1991.1-至今 清华大学生命科学学院（2009年9月以前为生物科学与技术系），教授、博导
● 研究兴趣、领域：
我们利用冷冻电子显微学，结合生物化学、生物物理学和细胞生物学等技术手段，研究：
（1）蛋白质复合体、复杂蛋白质机器和膜蛋白的结构、功能与工作机制；
（2）囊泡运输中的分子机制，蛋白质与膜脂的相互作用，生物膜与重大疾病的关系。
● 代表性论文：
1. li zq, chen s, zhao l, huang gq, xu h, yang xy, wang py, gao n, sui sf*. (2023) nuclear export of pre-60s particles through the nuclear pore complex. nature, 618(7964):411-418.
2. you x, zhang x, cheng j, xiao yn, ma jf, sun s, zhang xz*, wang hw*, sui sf*. (2023) in situ structure of the red algal phycobilisome–psii–psi–lhc megacomplex. nature, 616(7955):199-206.
3. sun s*, sui sf. (2023) structural insights into assembly of trappii and its activation of rab11/ypt32. curr opin struct biol., 80:102596. (review)
4. li zq, chen s, zhao l , huang gq, pi x , sun s, wang py, sui sf*. (2022) near-atomic structure of the inner ring of the saccharomyces cerevisiae nuclear pore complex. cell research, 32(5):437-450.
5. mi cc, zhang l, huang gq, shao g, yang f, you x, dong mq, sun s*, sui sf*. (2022) structural basis for assembly of trappii complex and specific activation of gtpase ypt31/32. science advances, 8(4):eabi5603.
6. xiao yn, huang gq, you x, zhu q, wang w, kuang ty, han h*, sui sf*, shen jr*. (2021) structural insights into cyanobacterial photosystem ii intermediates associated with psb28 and tsl0063. nat plants, 7(8):1132-1142.
7. sui sf*. (2021) structure of phycobilisomes. annu rev biophys., 50:53-72.
8. hu mq, yang f, huang yw, you x, liu d, sun s*, sui sf*. (2021) structural insights into the mechanism of human npc1l1-mediated cholesterol uptake. science advances, 7(29):eabg3188.
9. ma j, you x, sun s, wang x, qin s, sui sf*. (2020) structural basis of energy transfer in porphyridium purpureum phycobilisome. nature, 579(7797):146-151.
10. pi x, zhao s, wang w, liu d, xu c, han g, kuang t*, sui sf*, shen jr*. (2019) the pigment-protein network of a diatom photosystem ii-light-harvesting antenna supercomplex. science, 365(6452):eaax4406.
11. huang x, sun s, wang x, fan f, zhou q, lu s, cao y, wang qw, dong mq, yao j, sui sf*. (2019) mechanistic insights into the snare complex disassembly. science advances, 5(4):eaau8164.
12. qin x, pi x, wang w, han g, zhu l, liu m, cheng l, shen jr, kuang t*, sui sf*. (2019) structure of a green algal photosystem i in complex with a large number of light-harvesting complex i subunits. nat plants, 5(3):263-272.
13. pi x, tian l, dai he, qin x, cheng l, kuang t, sui sf*, shen jr*. (2018) unique organization of photosystem i-light-harvesting supercomplex revealed by cryo-em from a red alga. proc natl acad sci usa, 115(17):4423-4428.
14. zhang j, ma j, liu d, qin s, sun s*, zhao j, sui sf*. (2017) structure of phycobilisome from the red alga griffithsia pacifica. nature, 551(7678):57-63.
15. hu z, zhou q, zhang c, fan s, cheng w, zhao y, shao f, wang hw, sui sf*, chai j*. (2015) structural and biochemical basis for induced self-propagation of nlrc4. science, 350(6259):399-404.
● 凯发k8的联系方式：
电话： 86-10-62792083/62784768
e-mail: suisf@mail.tsinghua.edu.cn
lab website: http://suilab.life.tsinghua.edu.cn/
