recent representative papers-凯发k8
representative papers of school of life science
directed evolution and selection of biostable l-dna aptamers with a mirror-image dna polymerase
chen, ji; chen, mengyin; zhu, ting f.
nature biotechnology
cct2 is an aggrephagy receptor for clearance of solid protein aggregates
ma, xinyu; lu, caijing; chen, yuting; li, shulin; ma, ningjia; tao, xuan; li, ying; wang, jing; zhou, min; yan, yong-bin; li, pilong; heydari, kartoosh; deng, haiteng; zhang, min; yi, cong; ge, liang
cell
comprehensive maturity of nuclear pore complexes regulates zygotic genome activation
shen, weimin; gong, bo; xing, cencan; zhang, lin; sun, jiawei; chen, yuling; yang, changmei; yan, lu; chen, luxi; yao, likun; li, guangyuan; deng, haiteng; wu, xiaotong; meng, anming
cell
mirror-image t7 transcription of chirally inverted ribosomal and functional rnas
xu, yuan; zhu, ting f.
science
identification and receptor mechanism of tir-catalyzed small molecules in plant immunity
huang, shijia; jia, aolin; song, wen; hessler, giuliana; meng, yonggang; sun, yue; xu, lina; laessle, henriette; jirschitzka, jan; ma, shoucai; xiao, yu; yu, dongli; hou, jiao; liu, ruiqi; sun, huanhuan; liu, xiaohui; han, zhifu; chang, junbiao; parker, jane e.; chai, jijie
science
tir-catalyzed adp-ribosylation reactions produce signaling molecules for plant immunity
jia, aolin; huang, shijia; song, wen; wang, junli; meng, yonggang; sun, yue; xu, lina; laessle, henriette; jirschitzka, jan; hou, jiao; zhang, tiantian; yu, wenquan; hessler, giuliana; li, ertong; ma, shoucai; yu, dongli; gebauer, jan; baumann, ulrich; liu, xiaohui; han, zhifu; chang, junbiao; parker, jane e.; chai, jijie
science
translatome and transcriptome co-profiling reveals a role of tprxs in human zygotic genome activation
zou, zhuoning; zhang, chuanxin; wang, qiuyan; hou, zhenzhen; xiong, zhuqing; kong, feng; wang, qiujun; song, jinzhu; liu, boyang; liu, bofeng; wang, lijuan; lai, fangnong; fan, qiang; tao, wenrong; zhao, shuai; ma, xiaonan; li, miao; wu, keliang; zhao, han; chen, zi-jiang; xie, wei
science
advances and opportunities in rna structure experimental determination and computational modeling
zhang, jinsong; fei, yuhan; sun, lei; zhang, qiangfeng cliff
nature methods
structure of the nua4 acetyltransferase complex bound to the nucleosome
qu, keke; chen, kangjing; wang, hao; li, xueming; chen, zhucheng
nature
structure of human chromatin-remodelling pbaf complex bound to a nucleosome
yuan, junjie; chen, kangjing; zhang, wenbo; chen, zhucheng
nature
patterned cpcdh expression regulates the fine organization of the neocortex
lv, xiaohui; li, shuo; li, jingwei; yu, xiang-yu; ge, xiao; li, bo; hu, shuhan; lin, yang; zhang, songbo; yang, jiajun; zhang, xiuli; yan, jie; joyner, alexandra l.; shi, hang; wu, qiang; shi, song-hai
nature
metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex
dong, xiaoxiang; zhang, qiangqiang; yu, xiangyu; wang, ding; ma, jiaming; ma, jian; shi, song-hai
nature neuroscience
ultrasensitive ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development
xiong, zhuqing; xu, kai; lin, zili; kong, feng; wang, qiujun; quan, yujun; sha, qian-qian; li, fajin; zou, zhuoning; liu, ling; ji, shuyan; chen, yuling; zhang, hongmei; fang, jianhuo; yu, guang; liu, bofeng; wang, lijuan; wang, huili; deng, haiteng; yang, xuerui; fan, heng-yu; li, lei; xie, wei
nature cell biology
assembly of tetraspanin-enriched macrodomains contains membrane damage to facilitate repair
huang, yuwei; zhang, xing; wang, hong-wei; yu, li
nature cell biology
monocytes deposit migrasomes to promote embryonic angiogenesis
zhang, cuifang; li, tianqi; yin, shuyao; gao, mingyi; he, helen; li, ying; jiang, dong; shi, minghui; wang, jianbin; yu, li
nature cell biology
a trim66/dax1/dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells
zuo, feifei; jiang, junyi; fu, haipeng; yan, kun; liefke, robert; zhang, jing; hong, yaqiang; chang, zai; liu, nian; wang, zhanxin; xi, qiaoran
cell stem cell
the second polar body contributes to the fate asymmetry in the mouse embryo
jin, hongbin; han, yang; wang, huasong; li, j. xiao he; shen, weimin; zhang, lin; chen, luxi; jia, shunji; yuan, ping; chen, hui; meng, anming
national science review
context-dependent tumor-suppressive bmp signaling in diffuse intrinsic pontine glioma regulates stemness through epigenetic regulation of cxxc5
sun, ye; yan, kun; wang, yi; xu, cheng; wang, dan; zhou, wei; guo, shuning; han, yujie; tang, lei; shao, yanqiu; shan, shaobo; zhang, qiangfeng c.; tang, yujie; zhang, liwei; xi, qiaoran
nature cancer
malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate
zhao, mengjia; yao, pengbo; mao, youxiang; wu, jinjun; wang, weihua; geng, chenhui; cheng, jie; du, wenjing; jiang, peng
nature metabolism
an asia-specific variant of human igg1 represses colorectal tumorigenesis by shaping the tumor microenvironment
yang, bing; zhang, zhen; chen, xiangjun; wang, xu-yan; qin, shishang; du, liaoqi; yang, changjiang; zhu, liyu; sun, wenbo; zhu, yongjie; zheng, qinwen; zhao, shidong; wang, quan; zhao, long; lin, yilin; huang, jinghe; wu, fan; lu, lu; wang, fei; zheng, wenjie; zhou, xiao-hua; zhao, xiaozhen; wang, ziye; sun，xiao-lin; ye, yingjiang; wang, shan; li, zhanguo; qi, hai; zhang, zemin; kuang, dong-ming; zhang, lei; shen, zhanlong; liu, wanli
the journal of clinical investigation
chimeric crispr-casx enzymes and guide rnas for improved genome editing activity
tsuchida, connor a.; zhang, shouyue; doost, mohammad saffari; zhao, yuqian; wang, jia; o'brien, elizabeth; fang, huan; li, cheng-ping; li, danyuan; hai, zhuo-yan; chuck, jonathan; brötzmann, julian; vartoumian, araz; burstein, david; chen, xiao-wei; nogales, eva; doudna, jennifer a.; liu, jun-jie gogo
molecular cell